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From144US$ /night
Check-in
23Nov2025Select date
Check-out
24Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview and Details

3253 William Street, Cape Girardeau, Missouri, United States, 63701

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 By Ihg - All-suite hotel near Southeast Missouri State University

Located 10 km from Cape Girardeau Regional Airport, this hotel offers 102 suites with high-speed internet access. The property features a heated indoor pool open from 8 AM to 11 PM and a fitness center with treadmills and elliptical machines. Guests receive a complimentary Express Start Breakfast including eggs, pancakes, and cinnamon rolls. Business travelers benefit from the hotel's proximity to Procter & Gamble, Mondi, and Biokyowa, while two meeting rooms with audio/visual equipment are available for events. The hotel is wheelchair accessible throughout, with eight ADA-compliant rooms available.

Additional perks of the hotel

Free self-parking on all sides of the hotel

Coffee and tea service in the lobby

Business center with printing and copying services

Self-service laundry facilities open 24 hours

Cape Girardeau taxi services available

Close to downtown Main Street district historical sites

Near Show Me Center and Shawnee Park

Wall of Fame mural featuring 45 famous Missourians located nearby

Hotel Suites

All 102 accommodations are suites, many featuring pull-out sofas. King suites include whirlpool tubs in the bathrooms. Each suite is equipped with standard amenities including high-speed internet access, cable TV with premium channels, microwave, refrigerator, and wet bar. The rooms feature triple-sheeted bedding and are decorated in warm colors. Certain units include separate seating areas where guests can relax.

Other conveniences

Two-line phones with voicemail

Work desk with lamp and desk-level power outlets

Pillow menu and triple-sheeted bedding

Separate vanity area with hairdryer

Iron and ironing board

Large bath towels

Free local phone calls

120V and 220V AC power

Free bottled water

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Choose Your Room Category

The hotel offers a range of accommodations including doubles, family rooms, and suites—plus breakfast, free cancellation, and special rates.
King Suite Non-Smoking
5 persons
38 m² 
1 King-size bed
Heating
Air conditioning
Standard Room
2 persons
38 m² 
2 King Size Beds
Heating
Air conditioning
Deluxe Suite
2 persons
38 m² 
2 King Size Beds
Heating
Air conditioning
Standard Queen Room
2 persons
38 m² 
1 King-size bed
Heating
Air conditioning
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Room Availability and Pricing Calendar

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Navigating city

Available Transport Modes List

City Centre
Cape Girardeau 5.2 km
Airports
Cape Girardeau Regional (CGI) 9.9 km
Williamson County Regional (MWA) 99.9 km

Facilities

This hotel provides premium amenities for a memorable and relaxed stay

General

  • No smoking on site
  • Free Wi-Fi
  • Free parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Golf course

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Paid shuttle service
  • Housekeeping
  • Laundry
  • Shops/Commercial services

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Video games
  • Children's buffet
  • Board games

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Indoor swimming pool
  • Sun loungers
  • Casino
  • Spa centre

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Hotel Location

3253 William Street, Cape Girardeau, Missouri, United States, 63701
Map view
3253 William Street, Cape Girardeau, Missouri, United States, 63701
Nearby
Tilt
590 m
Restaurants
Popeyes Louisiana Kitchen
140 m
3237 William St
Yummy Asian Buffet
320 m
3254 William St
Chick-fil-A
510 m
3333 Gordonville Rd
Firehouse Subs
680 m
3047 William St Ste. 108
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Check-in
23Nov2025Select date
Check-out
24Nov2025Select date
Rooms and Guests2 Guests, 1 Room